Cognitive dysfunction in pediatric multiple sclerosis
نویسندگان
چکیده
منابع مشابه
Cognitive dysfunction in pediatric multiple sclerosis
Cognitive and neuropsychological impairments are well documented in adult multiple sclerosis (MS). Research has only recently focused on cognitive disabilities in pediatric cases, highlighting some differences between pediatric and adult cases. Impairments in several functions have been reported in children, particularly in relation to attention, processing speed, visual-motor skills, and langu...
متن کاملCognitive Dysfunction in Multiple Sclerosis
In Multiple Sclerosis (MS) prevalence studies of community and clinical samples, indicate that 45-60% of patients are cognitively impaired. These cognitive dysfunctions have been traditionally described as heterogeneous, but more recent studies suggest that there is a specific pattern of MS-related cognitive dysfunctions. With the advent of disease-modifying medications for MS and emphasis on e...
متن کاملPsychiatric diagnoses and cognitive impairment in pediatric multiple sclerosis.
BACKGROUND Pediatric multiple sclerosis (MS) represents approximately 5% of the MS population; information regarding clinical features is slowly accumulating. Cognitive and psychiatric impairments frequently occur, but remain poorly understood. OBJECTIVES To describe psychiatric diagnoses among children with MS referred for psychiatric assessment and their relation to cognitive impairment. ...
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Studies with conventional magnetic resonance imaging (MRI) support the hypothesis that cognitive impairment in multiple sclerosis (MS) patients is related with the lesion burden. Patterns of frontal lobe cognitive decline were also found to be related with the corresponding regional lesion load, although the total lesion load on T2-weighted MRI scans of the brain seems to be more relevant in de...
متن کاملDisconnection as a mechanism for cognitive dysfunction in multiple sclerosis.
Disconnection of cognitively important processing regions by injury to the interconnecting white matter provides a potential mechanism for cognitive dysfunction in multiple sclerosis. The contribution of tract-specific white matter injury to dysfunction in different cognitive domains in patients with multiple sclerosis has not previously been studied. We apply tract-based spatial statistics (TB...
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ژورنال
عنوان ژورنال: Neuropsychiatric Disease and Treatment
سال: 2014
ISSN: 1178-2021
DOI: 10.2147/ndt.s48495